Clinical application value and prospect of peripheral blood circulating microRNA in hepatocellular carcinoma
10.3760/cma.j.cn115355-20220412-00219
- VernacularTitle:肝癌外周血循环微RNA的临床应用价值与展望
- Author:
Shaohui MA
1
;
Wei CUI
;
Hongjun GAO
Author Information
1. 中国医学科学院北京协和医学院肿瘤医院检验科，北京 100021
- Keywords:
Carcinoma, hepatocellular;
Circulating microRNAs;
Tumor markers, biological;
Diagnosis;
Clinical monitoring
- From:
Cancer Research and Clinic
2023;35(3):223-228
- CountryChina
- Language:Chinese
-
Abstract:
Early diagnosis, effective treatment and monitoring of recurrence and metastasis of hepatocellular carcinoma have always been difficult problems for clinicians. MicroRNA (miRNA) plays an important role in hepatocellular carcinoma cells' proliferation, apoptosis, metabolism and other processes, and can be released into body fluids such as blood, urine and saliva. The peripheral blood miRNA in hepatocellular carcinoma can be used as biomarkers for the diagnosis, efficacy assessment, recurrence and metastasis monitoring and prognosis judgment, and may even become therapeutic targets for hepatocellular carcinoma. This article summarizes the research progress of circulating miRNA in peripheral blood as markers for diagnosis and treatment monitoring of hepatocellular carcinoma.
