Progress of relationship between autophagy and hepatocellular carcinoma
10.3760/cma.j.cn115355-20220831-00557
- VernacularTitle:自噬与肝细胞癌关系的研究进展
- Author:
Liyue FU
1
;
Jiuliang JIANG
;
Meng LIU
;
Junjun LI
;
Kaiping LIU
;
Zhenyu YU
;
Haitao ZHU
Author Information
1. 贵州医科大学临床医学院，贵阳 550001
- Keywords:
Hepatocellular carcinoma;
Autophagy;
Macro-autophagy;
Micro-autophagy;
Chaperone-mediated autophagy
- From:
Cancer Research and Clinic
2023;35(2):150-153
- CountryChina
- Language:Chinese
-
Abstract:
Autophagy is an intracellular degradation process that delivers cytoplasmic constituents to the lysosome. Abnormality of autophagy is related to many human diseases, which provides a new clue to the pathophysiology of human cancer. However, the role of autophagy in normal liver physiology and the pathogenesis of liver diseases need to be further clarified. This article reviews the role of autophagy in the occurrence and development of hepatocellular carcinoma and the molecular mechanisms.
