Targets of chimeric antigen receptor T-cell in breast cancer and the application progress
10.3760/cma.j.cn115355-20210811-00342
- VernacularTitle:嵌合抗原受体T细胞在乳腺癌中的作用靶点及其应用的研究进展
- Author:
Ping BI
1
;
Peng LI
;
Fuguo TIAN
Author Information
1. 山西医科大学第二临床医学院,太原 030001
- Keywords:
Chimeric antigen receptor T-cell;
Breast neoplasms;
Tumor epitope;
Tumor microenvironment
- From:
Cancer Research and Clinic
2023;35(1):73-77
- CountryChina
- Language:Chinese
-
Abstract:
Breast cancer is the most common malignant tumor in women. It is particularly important to seek targeted therapy other than surgery, chemoradiotherapy, endocrine therapy. With the continuous exploration of tumor immunotherapy, more and more therapeutic targets have been discovered. This paper reviews therapeutic targets of chimeric antigen receptor T-cell (CAR-T) and the application in breast cancer.