Acupuncture intervening depressive disorder:research progress in its neurobiological mechanism
- VernacularTitle:针刺干预抑郁症的神经生物学机制研究进展
- Author:
Pengfei LI
;
Min XIAO
;
Xuejiao MA
;
Xingke YAN
;
Chongbing MA
;
Jue HONG
- Keywords:
Acupuncture Therapy;
Brain;
Neurons;
Neuroglia;
Electrophysiology;
Depression
- From:
Journal of Acupuncture and Tuina Science
2023;21(3):239-246
- CountryChina
- Language:Chinese
-
Abstract:
Depressive disorder seriously affects people's physical and mental health.Acupuncture is a safe and effective treatment for depression,yet,its mechanism is unclear.Therefore,acupuncture's action mechanism in intervening depression was summarized from several perspectives,including morphology and ultrastructure of neurons in depression-related brain areas,function and structure of glial cells,brain functional and structural connectivity,and neuroelectrophysiology.It's discovered that acupuncture can repair the morphological and ultrastructural damage of neurons in the hippocampus and prefrontal lobe,mitigate the functional and structural injuries of glial cells in the hippocampus and prefrontal lobe,strengthen functional connectivity and heal structural connection,and promote neuroelectrophysiological activities,which possibly are the principal mechanisms of how acupuncture works in intervening depressive disorder.
