Clinical effect of radiofrequency introduction of tranexamic acid combined with Q-switched laser in the treatment of moderate to severe melasma
10.3760/cma.j.issn.1671-0290.2023.04.011
- VernacularTitle:氨甲环酸导入联合调Q激光治疗黄褐斑的效果
- Author:
Shuya BAI
1
;
Huan CUI
;
Huanhuan PAN
Author Information
1. 河南中医药大学第一附属医院整形美容科，郑州 450000
- Keywords:
Chloasma;
Tranexamic acid;
Radiofrequency introduction;
Q-switched laser;
Recrudescence
- From:
Chinese Journal of Medical Aesthetics and Cosmetology
2023;29(4):296-299
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To observe the clinical effect of tranexamic acid radiofrequency introduction combined with Q-switched laser comprehensive treatment of moderate to severe melasma.Methods:From December 2019 to September 2021, ninety-six female patients with melasma [age 24-59 years old, average age (37.8±6.0) years old] were admitted to the Plastic and Aesthetic Department of the First Affiliated Hospital of Henan University of Chinese Medicine. They were divided into the Q-switched laser group and the combined group by random number table method, with 48 cases respectively. The Q-switched laser group received Q-switched laser therapy, while the combined group received tranexamic acid radiofrequency introduction combined with Q-switched laser comprehensive therapy. The melasma area and severity index (MASI) scores were compared between the two groups before and after treatment. The clinical efficacy, adverse reactions and recurrence rates of the two groups were compared.Results:The MASI scores of the Q-switched laser group and the combined treatment group were (28.28±1.24) points and (28.52±4.25) points respectively before treatment, and (13.38±7.96) points and (9.11±5.48) points respectively after treatment. The MASI scores of the two groups were decreased after treatment, which of the combined group was lower than that of the Q-switched laser group ( t=3.06, P<0.05). The total clinical effective rate of the combination group (93.75%) was higher than that of the Q-switched laser group (79.17%) (χ 2=4.36, P<0.05). The incidence rate of hyperpigmentation (2.08%) and recurrence rate (2.08%) of the combination group were lower than those of the Q-switched laser group (14.58%, 16.67%) (χ 2=6.01, P<0.05). Conclusions:Tranexamic acid radiofrequency introduction combined with Q-switched laser comprehensive treatment can improve skin lesions and clinical efficacy in patients with moderate to severe melasma, and reduce pigmentation and recurrence.
