Clinical efficacy of botulinum toxin A in the treatment of hand hyperhidrosis
10.3760/cma.j.issn.1671-0290.2023.03.015
- VernacularTitle:A型肉毒毒素治疗手部多汗症的效果
- Author:
Xuguang LEI
1
;
Liying DAI
;
Bingyang YU
;
Xingxing CHEN
Author Information
1. 山东大学附属威海市立医院医疗美容科，威海 264200
- Keywords:
Hyperhidrosis;
Botulinum Toxin Type A;
Hand;
Injection;
Curative effect
- From:
Chinese Journal of Medical Aesthetics and Cosmetology
2023;29(3):227-230
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the clinical efficacy of botulinum toxin A in the treatment of hand hyperhidrosis.Methods:One hundred patients with hand hyperhidrosis were treated with botulinum toxin A (BTXA, Lanzhou Biotechnology Development Co., Ltd., Botulinum Toxin Type A for Injection Hengli) injection, a total of 200 U. Each hand was injected with 100 U respectively. The curative effect was evaluated by self-made questionnaire. The scores of the two were added. The subjective and objective evaluation were carried out before and after injection, and the patients were rechecked 2 weeks, and 1, 4 and 6 months after injection. Efficacy, patient satisfaction and adverse reactions were evaluated.Results:Compared with before treatment, the effective rate increased 2 weeks after injection, 1 month after injection, 4 months after injection and 6 months after injection, and the difference was statistically significant (Chi-square value was 31.54, 36.33, 28.34, 25.23, respectively, P<0.05). After 6 months of follow-up, the effect gradually decreased, and the curative effect could be maintained for about 10 months. After recurrence, the symptoms of hand sweating were still reduced. Satisfaction 96%; Adverse reactions were mild, subcutaneous blood stasis, 27% hand muscles were slightly weak, and returned to normal after 2-3 weeks. Conclusions:Botulinum toxin A injection has certain curative effect, high safety and less adverse reactions. It is an ideal method for the treatment of hand hyperhidrosis.
