Efficacy of autologous peripheral blood nucleated cell therapy on periocular wrinkles
10.3760/cma.j.issn.1671-0290.2023.03.006
- VernacularTitle:自体外周血有核细胞注射改善眶周皱纹的效果
- Author:
He QIU
1
;
Rui ZHAO
;
Shuo LIU
;
Lideng CAO
;
Hang WANG
Author Information
1. 四川大学华西口腔医院医疗美容科 口腔疾病研究国家重点实验室 国家口腔疾病临床医学研究中心，成都 610041
- Keywords:
Transplantation, autologous;
Injections;
Autologous peripheral blood nucleated cells;
Periocular wrinkles;
Periocular rejuvenation;
VISIA complexion analys
- From:
Chinese Journal of Medical Aesthetics and Cosmetology
2023;29(3):186-189
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To explore the clinical effect of dermal and subcutaneous injection of autologous peripheral blood nucleated cells in improving periocular wrinkles.Methods:Eighteen cases of beauty seekers who planned to improve periocular wrinkles were selected as the research objects of this study. Autologous nucleated cells and blood active components were isolated and purified by negative collection mixed method and evenly injected into the periocular skin of patients. VISIA image analysis system, and satisfactory score were used to detect and evaluate the related characteristics of periocular skin at different stages before and after treatment. The scores were compared and analyzed, and the complications after treatment were recorded.Results:The 18 patients were followed up. The score of VISIA periorbital static wrinkles decreased from (22.09±8.21) before treatment to (18.31±7.84) one month after treatment, and the difference was statistically significant ( t=-7.495, P<0.05). 17 patients were satisfied; After 3 months of follow-up, 15 cases were satisfied. The texture, consistency and pore state of periorbital skin were improved in some patients (10 cases). Conclusions:Autologous peripheral blood nucleated cell therapy can improve periorbital wrinkles, especially skin fine lines, and geta high satisfactory rate. There are almost no adverse reactions after the treatment, which is worthy of clinical application.
