Comparison of five therapeutic methods in treatment of moderate acne vulgaris
10.3760/cma.j.issn.1671-0290.2022.06.014
- VernacularTitle:5种方法治疗中度痤疮的疗效比较研究
- Author:
Ying TU
1
;
Hongjing JIANG
;
Cheng YANG
;
Xiaofeng HUANG
;
Jianting YANG
;
Li HE
Author Information
1. 昆明医科大学第一附属医院皮肤科，昆明 650032
- Keywords:
Acne vulgaris;
Moderate;
Minocycline;
Red-blue light;
Glycolic acid;
Intense pulsed light
- From:
Chinese Journal of Medical Aesthetics and Cosmetology
2022;28(6):500-504
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To observe the efficacy of drug combined with red-blue light irradiation, chemical peeling by glycolic acid and intense pulsed light (IPL) in the treatment of moderate acne vulgaris.Methods:A total of 187 patients with moderate acne vulgaris were divided into five groups. There were 59 males and 128 females, aged from 16 to 29 years (21.79±2.52). In group A, patients were treated with oral medicines; the patients were treated with oral medicines combined with red-blue light irradiation, chemical peeling by glycolic acid and IPL respectively in group B, group C and group D. In group E, patients were treated with oral medicines combined with chemical peeling by glycolic acid and IPL. The number of different types of skin lesions (comedoes, papules, pustules) were compared between before and after treatment in five groups. The clinical effect of five treatment groups was evaluated by comparing regression rates of different types of skin lesions and total skin lesions and treatment efficiency.Results:All the patients with moderate acne vulgaris were brought into this study. The regression rates of comedoes, papules and total skin lesions were (86.37±9.64)%, (94.25±9.79)% and (88.80±9.40)% respectively in group E, and significantly higher than that of other four groups ( P<0.05). The treatment efficiency of group E also were significantly higher than that of other four groups ( P<0.05). Then, the regression rates of comedoes (70.91±18.52) in group C was significantly higher than that of group A and group B ( P<0.05). The regression rates of papules (91.42±13.86) in group D was significantly higher than that of group A and group B ( P<0.05). Conclusions:Oral medicines combined with chemical peeling by glycolic acid and IPL has obvious clinical efficacy in treatment of patients with moderate acne vulgaris. Oral medicines combined with chemical peeling by glycolic acid can obviously improve comedoes, and oral medicines combined with IPL can obviously improve papules.
