Efficacy of fractional CO 2 laser and 1064-nm, Q-switched Nd∶YAG laser on xanthelasma palpebrarum
10.3760/cma.j.issn.1671-0290.2022.06.004
- VernacularTitle:点阵CO 2激光与Q开关1 064 nm掺钕钇铝石榴石晶体(Nd∶YAG)激光治疗睑黄瘤的效果
- Author:
Yue HUANG
1
;
Jin YUAN
;
Xiaoyan ZHAO
;
Kunli ZHOU
;
Guiqiong LI
;
Qiguo ZHANG
;
Xiugu TU
;
Liangqi CAI
Author Information
1. 厦门大学附属第一医院皮肤科，厦门大学医学院福建医科大学临床医学部，厦门 361002
- Keywords:
Eyelid neoplasms;
Treatment outcome;
Xanthelasma palpebrarum;
Randomized split-face controlled trial;
Fractional CO 2 laser;
Q-switch 1 064 nm Nd
- From:
Chinese Journal of Medical Aesthetics and Cosmetology
2022;28(6):463-466
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To determine the clinical efficacy and safety of a fractional CO 2 laser and a 1 064 nm, Q-switched Nd∶YAG laser therapy in the treatment of xanthelasma palpebrarum. Methods:From October 2020 to October 2021, 30 patients (5 males and 25 females) with bilateralxanthelasma palpebrarum of the eyelid were enrolled in the Department of Dermatology, the First Affiliated Hospital of Xiamen University. The age ranged from 38 to 67 (51±7) years. One side was randomly treated with fractional CO 2 laser as the fractional group, and the other side was treated with Q-switch 1 064 nm Nd∶YAG laser as the Q-switch group. The treatment was given every 28 days for 4 times. Before treatment and 1 month after the last treatment, the general pictures were taken to compare the clinical effect. Skin ultrasound was used to measure the difference of tumor thickness before and after treatment. The incidence of adverse reactions, such as local scar, hyperpigmentation or hypopigmentation after inflammation, were recorded. Results:Under general photos, there was statistically significant difference in efficacy scores between the two groups before and after treatment ( Z=-3.082, P<0.05). By comparison of tumor thickness under skin ultrasound, the difference between the two groups before and after treatment was statistically significant ( t=21.60, P<0.05; t=17.29, P<0.05); there was no statistically significant difference between the two groups before treatment ( t=0.46, P=0.650), but there was statistically significant difference between the two groups after treatment ( t=8.41, P<0.001). No serious adverse reactions occurred in both groups. Conclusions:Fractional CO 2 laser or Q-switch 1 064 nm Nd∶YAG laser can safely and effectively improve xanthelasma palpebrarum, in which the effect of fractional CO 2 laser is much better.
