Aplastic anemia and dental implant rehabilitation: a clinical trial.
10.5125/jkaoms.2015.41.5.265
- Author:
Jun Hwa KIM
1
;
Uttom Kumar SHET
;
Byeong Guk KIM
;
Myung In KIM
;
Min Suk KOOK
;
Hee Kyun OH
;
Sun Youl RYU
;
Hong Ju PARK
;
Seunggon JUNG
Author Information
1. Department of Oral and Maxillofacial Surgery, School of Dentistry, Chonnam National University, Gwangju, Korea. ashgray79@gmail.com
- Publication Type:Clinical Trial ; Case Report
- Keywords:
Aplastic anemia;
Dental implants;
Rehabilitation
- MeSH:
Adult;
Anemia, Aplastic*;
Dental Implants*;
Dentition;
Female;
Fibrosis;
Follow-Up Studies;
Hemorrhage;
Humans;
Iron;
Mandible;
Maxilla;
Osseointegration;
Rehabilitation*;
Tooth;
Wound Healing;
Wounds and Injuries
- From:Journal of the Korean Association of Oral and Maxillofacial Surgeons
2015;41(5):265-269
- CountryRepublic of Korea
- Language:English
-
Abstract:
The purpose of this study was to investigate implant-supported restoration as a technique for restoring missing teeth in patients with aplastic anemia. Recurrent bleeding from wound sites leads to persistent release of iron in the tissue. Excessive iron in tissue is related to clinical findings, including fibrosis, poor wound healing, and high level of angiogenesis, which are possible etiological factors of reduced osseointegration. A 44-year-old female patient with aplastic anemia was treated with multiple endosseous implants throughout the mandible and in the posterior region of the maxilla. After 14 implants were placed, radiological and clinical parameters were assessed during the follow-up period. Marginal bone did not change significantly during the follow-up period. The fine trabecular bone in intimate contact and enclosing the implant fixture was sufficient for successful osseointegration. None of the 14 implants were associated with compilations during the seven-year experimental period. This study suggests that dental implant procedures are a safe and reliable treatment option for restoration of missing dentition in patients with aplastic anemia.
