Research progress on the role and mechanisms of gut microbiota and related biomarkers in the pathogenesis of coronary heart disease
10.3760/cma.j.cn114452-20230119-00035
- VernacularTitle:肠道菌群在冠心病中的作用机制及生物标志物应用进展
- Author:
Qiuyue XU
1
;
Yong DUAN
Author Information
1. 昆明医科大学第一附属医院医学检验科 云南省检验医学重点实验室 云南省医学检验临床研究中心，昆明650032
- Keywords:
Atherosclerosis;
Cardiovascular diseases;
Intestinal flora;
Metabolite;
Biomarker
- From:
Chinese Journal of Laboratory Medicine
2023;46(7):748-753
- CountryChina
- Language:Chinese
-
Abstract:
Coronary heart disease (CHD) has become a major public health issue in China. Gut microbiota has gradually become a CHD research hotspot in terms of auxiliary diagnosis, treatment and prevention targets. Results from multiple studies have shown that gut microbiota dysbiosis may mediate the process of CHD directly or indirectly through their metabolites, and some intestinal probiotics could inhibit the progression of atherosclerosis. The research advances on the related mechanism and their diagnostic efficacy as biomarkers of gut microbiota and metabolites in CHD are reviewed here to provide a reference for current and future clinical application.
