Research progress on clustered regularly interspaced short palindromic repeats-associated 9 system for the treatment of HSV
10.3760/cma.j.cn114452-20230320-00157
- VernacularTitle:聚类规则间隔短回文重复序列及其相关蛋白9系统用于单纯疱疹病毒治疗的研究进展
- Author:
Chenchen CHU
1
;
Ling JI
;
Wenhua ZHOU
Author Information
1. 潍坊医学院医学检验学院，潍坊 261053
- Keywords:
Simplexvirus;
CRISPR/Cas9;
Gene editing;
Rapid diagnostic technology
- From:
Chinese Journal of Laboratory Medicine
2023;46(5):524-528
- CountryChina
- Language:Chinese
-
Abstract:
Herpes simplex virus (HSV) is a double-stranded DNA enveloped virus that causes severe effects on the human body by infecting the skin and nerve tissues. Because of latency and reactivation, the rapid detection and eradication of HSV are great challenges for clinical treatments. In recent years, clustered regularly interspaced short palindromic repeats (CRISPR)/CRISPR-associated 9 (Cas9) system has developed rapidly in the field of gene editing and detection due to its simple design and high targeting efficiency.
