Application progress of microfluidic chip in isolation and capture of circulating tumor cells
10.3760/cma.j.cn114452-20230202-00064
- VernacularTitle:微流控芯片在循环肿瘤细胞分离捕获中的应用进展
- Author:
Duo YANG
1
;
Hao LIANG
Author Information
1. 大连大学机械工程学院，大连116622
- Keywords:
Circulating tumor cell;
Microfluidic chip;
Separation of capture
- From:
Chinese Journal of Laboratory Medicine
2023;46(4):428-432
- CountryChina
- Language:Chinese
-
Abstract:
The amount of circulating tumor cells(CTC) in peripheral blood is very small, which is difficult to isolate. Microfluidic chips are becoming a hot area in recent years because of their portability, high sensitivity, high capture,and low cost. Microfluidic devices have been shown to maintain optimal performance for CTC isolation capture, including flux, purity, recovery, and clinical relevance. However, microfluidic technology is still unable to recover CTC with high recovery and purity.
