ICP-MS establishes blood lead reference method expected to improve detection accuracy

VernacularTitle:建立ICP-MS的血铅参考方法可提高检测准确性
Author: Mengyu XU ¹ ; Weiyan ZHOU ; Yuhang DENG ; Jie ZENG ; Chuanbao ZHANG
Author Information

1. 北京医院　国家老年医学中心，国家卫生健康委临床检验中心，中国医学科学院老年医学研究院　中国医学科学院北京协和医学院，北京　100730
Keywords: Lead poisoning; Reference standards; Inductively coupled plasma mass spectrometry; Environmental monitoring
From: Chinese Journal of Laboratory Medicine 2023;46(2):225-230
CountryChina
Language:Chinese
Abstract: Lead poisoning severely threatens human health with its cumulation and durability in the body. The analysis of lead in blood is vital for screening, diagnosis, treatment, and prognostication of lead poisoning and for indirectly monitoring the level of lead in the environment. Although the detection programs are available throughout our country, the accuracy and comparability of the results cannot meet the expectation. A variety of factors can affect the accuracy of blood lead testing. To promote the application of blood lead analysis in clinical trials and reduce the bias of results, a better reference system for blood lead analysis should be established to evaluate the accuracy of traditional methods, promote the standardization of blood lead analysis and achieve accurate blood lead testing.