Research progress of hydroxychloroquine retinopathy
10.3760/cma.j.cn511434-20220215-00087
- VernacularTitle:羟氯喹视网膜病变的研究进展
- Author:
Jia LIANG
1
;
Dong FANG
;
Lu CHEN
;
Ting XIE
;
Pengxue WEI
;
Shaochong ZHANG
Author Information
1. 深圳市眼科医院 暨南大学附属深圳眼科医院 深圳市眼病防治研究所, 深圳 518040
- Keywords:
Hydroxychloroquine retinopathy;
Drug toxicity;
Pathogenesis;
Clinical manifestations;
Multimodal imaging;
Disease management;
Review
- From:
Chinese Journal of Ocular Fundus Diseases
2023;39(6):515-519
- CountryChina
- Language:Chinese
-
Abstract:
Hydroxychloroquine is widely used in a variety of autoimmune diseases. However, long-term use of hydroxychloroquine can cause severe retinopathy, which has a complex pathogenic mechanism and diverse clinical manifestations, mainly manifested as photoreceptor and retinal pigment epithelial damage and irreversible vision loss. Identifying damage before retinitis pigment epithelium lesions preserve central vision, so early detection is crucial to slow disease progression and reduce vision loss. The development of multimodal imaging technology and the issuance of the latest treatment guidelines provide a powerful tool for the early screening and treatment of hydroxychloroquine retinopathy. Proficient in the latest guidelines for the treatment of hydroxychloroquine can better guide clinicians to do a good job in disease screening and management, recommend risks, safe dosages and appropriate screening procedures to patients and strengthen the prevention of hydroxychloroquine retinopathy, which will help save the vision of more patients and reduce the waste of medical resources.
