Advances in application of optical coherence tomography angiography for quantitative analysis in central serous chorioretinopathy
10.3760/cma.j.cn511434-20230208-00050
- VernacularTitle:光相干断层扫描血管成像在中心性浆液性脉络膜视网膜病变量化研究中的应用
- Author:
Qiaozhu ZENG
1
;
Yuou YAO
;
Shu TU
;
Mingwei ZHAO
Author Information
1. 北京大学人民医院眼科 眼病与视光医学研究所 视网膜脉络膜疾病诊治研究北京市重点实验室 北京大学医学部眼视光学院, 北京 100044
- Keywords:
Optical coherence tomography angiography;
Central serous chorioretinopathy;
Quantitative analysis;
Pathophysiology;
Treatment;
Review
- From:
Chinese Journal of Ocular Fundus Diseases
2023;39(4):347-354
- CountryChina
- Language:Chinese
-
Abstract:
Central serous chorioretinopathy (CSC) is one of the representative pachychoroid spectrum disease. Although fundus fluorescein angiography and indocyanine green angiography can be used as the gold standard for the diagnosis of CSC, they are invasive examinations, which may bring certain risks in clinical application and cannot help us obtain quantitative parameters. Optical coherence tomography angiography (OCTA), as a non-invasive and quantitative examination, is an important imaging tool for understanding the pathogenesis, diagnosis and treatment of CSC. With the advancement of OCTA, the swept-source OCTA has a satisfying scanning depth, a wider scanning range and a higher resolution. The development of OCTA broadens the horizons of the pathogenesis of CSC, promotes the understanding of the pathophysiology of CSC, and sheds new light for its clinical diagnosis and treatment. Based on OCTA, the choroid and retina in eyes with CSC are presented with qualitative and quantitative changes in vascular system. OCTA-guided CSC treatment and the discovery of prognostic markers based on OCTA challenge the application of traditional imaging techniques in CSC. With the continuous improvement and progress of OCTA technology, traditional angiography combined with OCTA will bring great benefits to the diagnosis and treatment of CSC. This review summarizes the quantitative application of OCTA in the pathogenesis, diagnosis and treatment of CSC.
