The influence of COVID-19 infection on treatments of patients with acute type A aortic dissection
10.3760/cma.j.cn112434-20230203-00022
- VernacularTitle:新型冠状病毒感染对急性A型主动脉夹层患者救治的影响
- Author:
Chenhan ZHANG
1
;
Yi YANG
;
Haiou HU
;
Yipeng GE
;
Zhiyu QIAO
;
Chengnan LI
;
Jun ZHENG
;
Yongmin LIU
;
Junming ZHU
Author Information
1. 首都医科大学附属北京安贞医院主动脉外科中心，北京 100029
- Keywords:
Aortic dissection;
COVID-19;
Outcomes of aortic surgery;
Omicron variants
- From:
Chinese Journal of Thoracic and Cardiovascular Surgery
2023;39(7):393-397
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the differences in outcomes of surgical strategies and prognosis of patients with acute type A aortic dissection(ATAAD) during the period of COVID-19 Omicron variant epidemic compared with the non-epidemic period.Methods:Clinical data were retrospectively collected from ATAAD patients during the COVID-19 Omicron variant epidemic(December 7, 2022 to January 10, 2023) and during the non-epidemic period(December 7, 2019 to January 10, 2020) to compare the differences in surgical strategies, perioperative mortality, and perioperative complication rates in ATAAD patients during the two different periods.Results:There were 14 patients in the COVID-19 infected group and 43 patients in the control group. Patients in the infected group had a shorter mean aortic clamp time[(89.71±16.27)min vs.(110.09±28.99)min, P<0.01], a significantly higher postoperative mortality rate relative to the control group(21.43% vs. 2.33%, P=0.02), a significantly longer length of stay in the ICU(3 days vs. 2 days, P=0.04) and the duration of intubation time(34 h vs. 14 h, P<0.01), and the incidence of adverse events, mainly cerebral infarction, was higher in infected group(28.57% vs. 6.98%, P=0.03). Conclusion:During the COVID-19 Omicron variant strain epidemic, our center preferred a more conservative surgical strategy in COVID-19 infected patients. Although the COVID-19 infection increased the postoperative mortality and complication rate of ATAAD, patients still achieve a more satisfactory outcome. Therefore, surgical treatment should be timely performed for ATAAD patients.
