Mechanism and prevention of structural valve degeneration and Bioprosthetic valve failure
10.3760/cma.j.cn112434-20211226-00416
- VernacularTitle:人工生物瓣膜退化衰败的机制及预防
- Author:
Qing CHU
1
;
Huawei GAO
Author Information
1. 中国医学科学院阜外医院心外科，北京 100037
- From:
Chinese Journal of Thoracic and Cardiovascular Surgery
2023;39(3):180-185
- CountryChina
- Language:Chinese
-
Abstract:
Structural valve degeneration (SVD) and bioprosthetic valve failure (BVF) seriously limits the service life of biological valves. Exploring the molecular mechanism and pathological process of SVD and BVF is an important way to improve valve durability and prognosis of patients with biological valves replacement. In this review, we systematically summarized the definition, pathogenesis, related molecular pathways and prevention strategies of SVD and BVF. This review is expected to provide a theoretical basis for the study of the mechanism of SVD and BVF and the development of clinical intervention targets.
