Diagnostic and therapeutic value of endoscopy and mucosal histology for digestive tract diseases in infants
10.3760/cma.j.cn321463-20230122-00209
- VernacularTitle:内镜及黏膜组织学检查在婴儿消化道疾病中的诊疗价值
- Author:
Weiwei LIAO
1
;
Xuemei ZHONG
;
Xin MA
;
Youzhe GONG
;
Huijuan NING
;
Yanling ZHANG
;
Jizhen ZOU
Author Information
1. 首都儿科研究所附属儿童医院消化内科，北京 100020
- Keywords:
Infant;
Endoscopy, gastrointestinal;
Gastric mucosa;
Histology
- From:
Chinese Journal of Digestive Endoscopy
2023;40(6):444-448
- CountryChina
- Language:Chinese
-
Abstract:
Objectives:To investigate the clinical value of endoscopy and mucosal histology for digestive tract diseases in infants.Methods:Clinical data of 357 infants who underwent 422 gastrointestinal endoscopies from January 2010 to December 2021 were collected. The indications, endoscopic manifestations, histological features of mucosa and diagnosis were analyzed.Results:A total of 159 gastroscopies and 263 colonoscopies were performed. Diarrhea (185 cases), bloody stool (178 cases) and vomiting (46 cases) were common symptoms. Endoscopy showed manifestations including non-specific inflammatory changes (265 cases), ulcer-like changes (72 cases), and normal mucusa (48 cases). A total of 373 biopsies were performed, including 260 cases of abnormal mucosal histology, 109 cases of normal mucosal histology, and 4 cases of too small biopsy specimens for analysis. Diagnoses were 208 cases of anaphylactic disease, 45 cases of inflammatory bowel disease, 15 cases of variation of structure, 10 cases of intestinal lymphangiectasis, 2 cases of autoimmune enteropathy, and 1 case of celiac disease. There was only 1 colonic perforation complicating endoscopy in terms of endoscopic complication.Conclusions:It is safe and effective to perform endoscopy standardly for digestive tract diseases in infants. Endoscopy with biopsies is a greatly informative test for diagnosis in infants.
