Gastric preparation with Sprite Zero ? for magnetically controlled capsule endoscopy
10.3760/cma.j.cn321463-20210820-00514
- VernacularTitle:“雪碧零卡 ?”在磁控胶囊内镜胃准备方案中的应用初探
- Author:
Jiahui ZHU
1
;
Yangyang QIAN
;
Xiao LIU
;
Bin JIANG
;
Zhuan LIAO
;
Zhaoshen LI
Author Information
1. 海军军医大学长海医院消化内科，上海 200433
- Keywords:
Capsule endoscopes;
Clinical trial;
Gastric preparation;
Sprite Zero
- From:
Chinese Journal of Digestive Endoscopy
2022;39(12):972-977
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To explore the feasibility of 400 mL Sprite Zero ? in gastric preparation for magnetically controlled capsule endoscopy (MCE) . Methods:A randomized controlled trial at the Department of Gastroenterology of Changhai Hospital, Naval Medical University from December 16th, 2019 to January 15th, 2020 was conducted. The patients and healthy volunteers who intended to receive MCE were randomly divided into the Sprite Zero ? (S) group and the water (W) group at 1∶1. For subjects in the W group, 800 mL water was taken 10 minutes before swallowing the capsule. And for subjects in the S group, 400 mL Sprite Zero ? was taken. The primary endpoint was gastric filling score and the secondary endpoint included the fullness score, gastric transit time (GTT), small bowel transit time (SBTT), completion rate (CR) for small bowel examination and the diagnostic yield. Results:A total of 102 subjects were enrolled, 52 subjects in the S group and 50 subjects in the W group. The median score of gastric filling was 4 at 0-5 min, >5-10 min and >10-15 min after taking the capsule in both groups, with less median liquid consumption in the S group than the W group (500 mL VS 950 mL, P<0.001). The S group showed lower median fullness score (7.0 scores VS 7.5 scores, P=0.030) and higher proportion of patients with GTT less than 30 minutes [69.57% (16/52) VS 27.59% (8/29), P=0.030] compared with the W group. The CR of small bowel examination in the S group was 100.00%, higher than that of the W group (89.66%, P=0.245). Conclusion:Compared with 800 mL water, 400 mL Sprite Zero ? can fully fill the stomach with more comfort. It has the potential to accelerate gastric emptying and improve the CR of small bowel examination, which is feasible for the gastric preparation.
