Efficacy of endoscopic ligation resection and endoscopic submucosal excavation for small gastrointestinal stromal tumors originating from muscularis propria
10.3760/cma.j.cn321463-20211220-00281
- VernacularTitle:内镜套扎切除术和内镜黏膜下挖除术治疗固有肌层起源小胃肠间质瘤的疗效分析
- Author:
Chunhong WEN
1
;
Jiang LIU
;
Qinglin TANG
;
Ming MA
;
Huiming LIN
;
Lixin DENG
;
Zhicong ZENG
;
Shuai ZHANG
;
Xuejuan HUANG
;
Mingqing ZHANG
Author Information
1. 中国人民解放军联勤保障部队第九〇九医院 厦门大学附属东南医院消化内科，漳州363000
- Keywords:
Gastrointestinal stromal tumors;
Endoscopes, gastrointestinal;
Endoscopic ligation resection;
Endoscopic submucosal excavation
- From:
Chinese Journal of Digestive Endoscopy
2022;39(11):921-924
- CountryChina
- Language:Chinese
-
Abstract:
Clinical data of 43 patients who underwent endoscopic resection for gastrointestinal stromal tumors (GIST) of length ≤1.2 cm at the Digestive Endoscopy Center of the 909th Hospital from January 2016 to December 2018 were retrospectively analyzed. The patients were divided into the endoscopic ligation resection (ELR) group ( n=27) and the endoscopic submucosal excavation (ESE) group ( n=16). The general, perioperative and follow-up data of the two groups were compared. The results showed that there was no significant difference in the general data between the two groups. The operation time was 20.0 (18.0,25.0) min in the ELR group and 27.5 (23.0,37.5) min in the ESE group, showing significant difference ( U=92.5, P=0.001). The en bloc resection rates were 100.0% (27/27) in the ELR group and 81.3% (13/16) in the ESE group, showing significant difference ( P=0.045). The postoperative hospital stays were 3 (2,4) days in the ELR group and 5 (4,6) days in the ESE group, showing significant difference ( U=125.5, P=0.020). There was no significant difference in the intraoperative bleeding rate, intraoperative hemorrhage volume, intraoperative perforation rate, number of hemostatic clips or postoperative complications including hemorrhage, fever and peritonitis between the two groups ( P>0.05). During the follow-up, there was no recurrence or metastasis of GIST in both groups. ELR and ESE can be safe and effective for small GIST ≤1.2 cm in diameter. Compared with the ESE group, the operation time and postoperative hospital stay are shorter with higher en bloc resection rate in the ELR group.
