Programmed cell death induced by Klebsiella pneumoniae infection
10.3760/cma.j.cn112309-20221224-00410
- VernacularTitle:肺炎克雷伯菌感染中的宿主细胞程序性死亡
- Author:
Zhongyu HAN
1
;
Banjiu ZHAXI
;
Jiajia ZHENG
Author Information
1. 北京大学第三医院检验科，北京 100191
- Keywords:
Programmed cell death;
Klebsiella pneumoniae;
Host-pathogen interaction;
Immune escape;
Infection treatment
- From:
Chinese Journal of Microbiology and Immunology
2023;43(4):327-332
- CountryChina
- Language:Chinese
-
Abstract:
Klebsiella pneumoniae can cause a variety of infectious diseases, especially in immunocompromised population. The emergence of multidrug-resistant hypervirulent Klebsiella pneumoniae has greatly limited the choice of treatment for Klebsiella pneumoniae infection, and the exploration of new treatment strategies is imminent. In the process of infection, there is a complex interaction between the programmed cell death of host cells and the invasion of Klebsiella pneumoniae. This paper mainly reviewed the research progress in several mechanisms of programmed cell death such as pyroptosis, apoptosis, necroptosis and autophagy caused by Klebsiella pneumoniae.
