IL-22 and immunity in female reproductive tract
10.3760/cma.j.cn112309-20221025-00355
- VernacularTitle:IL-22与女性生殖道免疫
- Author:
Ruqian ZHAO
1
;
Yuqin ZANG
;
Huanrong LI
;
Shiqi LIU
;
Yingmei WANG
;
Fengxia XUE
Author Information
1. 天津医科大学总医院妇产科，天津 300052
- Keywords:
IL-22;
Infection;
Polycystic ovary syndrome;
Endometriosis;
Tumor
- From:
Chinese Journal of Microbiology and Immunology
2023;43(4):322-326
- CountryChina
- Language:Chinese
-
Abstract:
IL-22 is a member of IL-10 cytokine family. In recent years, increasing evidence has shown that IL-22 is closely related to the immunity in female reproductive tract, and its role in disease development is two-sided. It can not only maintain the balance of microbiota, enhance the resistance to pathogens and reduce the tissue damage caused by infection, but also promote the development and progression of malignant diseases via various signaling pathways. More studies on the biological characteristics and functions of IL-22 are needed for clarifying the pathogenic mechanism and providing new insight into the diagnosis and treatment of female reproductive tract diseases.
