Progress in the relationship between intestinal fungal dysbiosis and digestive system tumors

VernacularTitle:肠道真菌失调和消化系肿瘤关系的研究进展
Author: Chenyi ZHANG ¹ ; Jingyuan FANG
Author Information

1. 上海交通大学医学院附属仁济医院消化科，上海市消化疾病研究所，上海　200001
Keywords: Fungal dysbiosis; Digestive system tumors; Tumorigenesis and progression; Treatment
From: Chinese Journal of Microbiology and Immunology 2023;43(3):243-247
CountryChina
Language:Chinese
Abstract: Intestinal fungal dysbiosis is closely associated with the development and progression of many diseases including tumors. The disruption of fungal communities is involved in tumorigenesis and progression through inducing aberrant host immune responses and the production of certain metabolites as well as promoting the establishment of interactions with bacteria. Fungal dysbiosis is a potential marker for early detection of digestive tumors and a factor influencing the efficacy of tumor therapy. Studying the association between gut fungi and digestive tumors may facilitate the prevention, diagnosis and treatment of digestive tumors.