Effects of transcranial magnetic stimulation combined with radiofrequency ablation of dorsal root ganglia in the treatment of herpes zoster neuralgia
10.3760/cma.j.issn.0254-1424.2023.06.010
- VernacularTitle:经颅磁刺激联合背根神经节脉冲射频治疗带状疱疹神经痛的疗效观察
- Author:
Jing WANG
1
;
Rong TAO
;
Songhe MA
;
Zhuoya MA
;
Lingjie XIA
;
Weisheng ZHUANG
Author Information
1. 河南省人民医院（郑州大学人民医院）疼痛科，郑州 450003
- Keywords:
Transcranial magnetic stimulation;
Radio frequency ablation;
Dorsal root ganglia;
Neuralgia
- From:
Chinese Journal of Physical Medicine and Rehabilitation
2023;45(6):528-532
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To observe the clinical efficacy of combining repeated transcranial magnetic stimulation (rTMS) with radiofrequency ablation (RF) of dorsal root ganglia in treating herpes zoster infection and neuralgia.Methods:Eighty-four individuals with a herpes zoster infection who had suffered from neuralgia for no more than 7 days were divided randomly into a control group, an rTMS group, an RF group, and an observation group, each of 21. All were treated with gabapentin, valciclovir and mecobalamin. The rTMS group received rTMS treatment, 5 days per week, for 2 consecutive weeks. The RF group received RF treatment of the dorsal root ganglia on the 15th day after enrollment, while the observation group received only the medication. Before the experiment as well as after 3, 7, 16, 30 and 60 days, all of the subjects self-assessed their discomfort using a pain visual analog scale (VAS). The Hamilton Depression Scale (HAMD), Hamilton Anxiety Scale (HAMA), Quality of Life Assessment Scale (QOL-SF36), and Pittsburgh Sleep Quality Index (PSQI) were also administered.Results:The average VAS, HAMA, HAMD, QOL-SF36, and PSQI scores of the observation group improved continuously and significantly during and after the treatment. Beyond 16 days all of those results were significantly better than the control group′s averages, and the observation group′s average VAS, HAMA and HAMD results were also significantly better than those of the rTMS group. The observation group′s average VAS, HAMA, HAMD and PSQI scores had improved significantly more than the RF group′s averages beyond 30 days.Conclusion:Combining rTMS and dorsal root ganglion RF can effectively alleviate the early pain symptoms of herpes zoster infection and neuralgia, relieve anxiety and depression, and significantly improve sleep and life quality. Such therapy is worthy of clinical promotion and application.
