Effects of high-intensity interval training on glycemia and the pancreatic β-cell functioning of persons with type 2 diabetes
10.3760/cma.j.issn.0254-1424.2022.12.006
- VernacularTitle:高强度间歇训练对2型糖尿病患者血糖控制及胰腺β细胞功能的影响
- Author:
Wangli ZHANG
1
;
Hanqing ZU
;
Chenyu WANG
;
Naixin CAO
Author Information
1. 郑州升达经贸管理学院体育学院，郑州 451191
- Keywords:
Interval training;
Diabetes mellitus;
Glycemic control;
Pancreatic β-cells;
Body composition
- From:
Chinese Journal of Physical Medicine and Rehabilitation
2022;44(12):1084-1089
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To explore any effect of 8 weeks of high-intensity interval training (HIIT) on glycemia and pancreatic β-cell function among persons with type 2 diabetes to provide data for optimizing their exercise protocol.Methods:Sixty patients with type 2 diabetes and without a habit of regular exercise were randomly divided into an exercise group ( n=30) and a control group ( n=30). Both groups maintained their daily living habits, except that the exercise group practiced HIIT on a power vehicle ergometer 3 times a week for 8 weeks. Before and after the intervention, the 2-hour oral glucose tolerance test (OGTT) was conducted to evaluate glycemia and pancreatic β-cell function. Body composition was also detected using dual-energy X-ray absorptiometry. Results:After the intervention a significant decrease was observed in the fasting blood glucose, mean blood glucose, glycosylated hemoglobin, blood glucose levels at the end of a 2h OGTT, blood glucose area under the curve and homeostatic model assessment of insulin resistance, as well as waist circumference and abdominal fat content of the exercise group. And there was a significant increase in the homeostatic model assessment of pancreatic β-cell function and disposition index among the exercise group. In the control group no significant differences were observed.Conclusion:Eight weeks of HIIT can improve glycemia and pancreatic β-cell function and reduce abdominal fat among persons with type 2 diabetes. It can be used as an effective rehabilitation protocol.
