Prenatal diagnosis and intrauterine treatment of a giant fetal hepatic hemangioma:a case report
10.3760/cma.j.cn113903-20220614-00634
- VernacularTitle:产前诊断并宫内治疗胎儿巨大肝血管瘤1例
- Author:
Hui TANG
1
;
Chaoxiang YANG
;
Jingshu LI
;
Wei WANG
;
Dan CHEN
;
Jing WU
Author Information
1. 广东省妇幼保健院医学遗传中心，广州 511400
- Keywords:
Liver neoplasms;
Hemangioma;
Prenatal diagnosis;
Fetal therapies
- From:
Chinese Journal of Perinatal Medicine
2023;26(4):331-334
- CountryChina
- Language:Chinese
-
Abstract:
This article reported a case of fetal giant hepatic hemangioma with cardiomegaly managed with intrauterine treatment. At 23 weeks of gestation, the patient was referred to Guangdong Women and Children Hospital due to abnormal abdominal echogenicity of the fetus, which was suspected to be a hepatic hemangioma or a hepatic arteriovenous fistula. The prenatal ultrasound at 26 weeks of gestation revealed an enlarged fetal hepatic hemangioma of 45 mm×35 mm×42 mm and an enlarged heart (cardiothoracic area ratio of 0.50). So, with the patient's informed consent, the fetus was treated with intrauterine administration of propranolol and dexamethasone and closely monitored by ultrasound. The volume of the lump still increased at the beginning of the medication, but started to shrink in the 7th week. Besides, the fetal cardiac load was reduced and the condition was controlled. The patient delivered at 37 weeks of gestation. The baby received a CT examination on the fourth day after birth which revealed an abdominal mass of 40 mm×30 mm×44 mm requiring no treatment, and no abnormalities were reported during a one-year follow-up.
