Progress on ferroptosis in pregnancy-related diseases

VernacularTitle:铁死亡在妊娠相关疾病中的研究进展
Author: Yaoxi XIONG ¹ ; Chao CHEN ; Jinyu LIU ; Xingyu YANG ; Weiwei CHENG
Author Information

1. 上海交通大学医学院附属国际和平妇幼保健院产科，上海　200030
Keywords: Ferroptosis; Pre-eclampsia; Diabetes, gestational; Pregnancy complications
From: Chinese Journal of Perinatal Medicine 2023;26(2):164-168
CountryChina
Language:Chinese
Abstract: Ferroptosis, a new form of programmed cell death, could be regulated by lipid metabolism, amino acid metabolism, and iron metabolism. Ferroptosis is closely related to human physiological mechanisms and involved in the development and progression of multiple diseases. More and more researchers have found that ferroptosis also plays a vital role in pregnancy-related disorders such as preeclampsia, gestational diabetes, and miscarriage. However, the mechanisms have not yet been fully understood. This article reviews the progress in ferroptosis in pregnancy-related diseases to provide new directions for scientific research and clinical treatment.