A case of survived extremely preterm infant with severe bronchopulmonary dysplasia after comprehensive therapy
10.3760/cma.j.cn113903-20220707-00693
- VernacularTitle:重度支气管肺发育不良超早产儿综合救治存活1例
- Author:
Ruiwei GAO
1
;
Ke ZHANG
;
Weiling KONG
;
Chao CHEN
;
Yun CAO
;
Jianguo ZHOU
Author Information
1. 国家儿童医学中心（复旦大学附属儿科医院）新生儿科，上海 201102
- Keywords:
Bronchopulmonary dysplasia;
Glucocorticoids;
Ureaplasma urealyticum;
Gastrostomy;
Combined modality therapy;
Infant, premature
- From:
Chinese Journal of Perinatal Medicine
2023;26(2):159-163
- CountryChina
- Language:Chinese
-
Abstract:
This article reported the comprehensive management of an extremely preterm infant with severe bronchopulmonary dysplasia. The patient born at 26 +6 gestational weeks was transferred to Children's Hospital of Fudan University due to invasive mechanical ventilation dependence at 61 d after birth and was diagnosed with severe bronchopulmonary dysplasia. A comprehensive treatment plan was adopted, including appropriate fluid restriction, improving nutrition, glucocorticoid administration, using antibiotics against Ureaplasma urealyticum infection to reduce pulmonary parenchymal lesions and alleviating pulmonary hypertension. The preterm infant was successfully extubated to non-invasive ventilation and subsequently weaned to a high-flow nasal cannula. Then, the patient was discharged at 372 d after birth (correct gestational age nine months and six days). At the 3-month follow-up after discharge, the patient remained on high-flow oxygen, but with lower flow and concentration of oxygen. Moreover, the growth, development and lung images were significantly improved. Follow-up to correct gestational age one year and 11 months, the child was not on oxygen any more, but on rehabilitation due to language and motor development retardation.
