Effects of antenatal corticosteroids exposure on multiple systems of preterm infants: a review
10.3760/cma.j.cn113903-20220513-00474
- VernacularTitle:产前糖皮质激素暴露对早产儿多系统影响的研究进展
- Author:
Xueqi BAI
1
;
Zhonghua SHI
Author Information
1. 南京医科大学第四临床医学院,南京 210029
- Keywords:
Prenatal exposure delayed effects;
Glucocorticoids;
Infant, premature;
Nervous system;
Cardiovascular system;
Root cause analysis
- From:
Chinese Journal of Perinatal Medicine
2023;26(1):72-77
- CountryChina
- Language:Chinese
-
Abstract:
Administration of antenatal corticosteroids (ACS) to pregnant women at risk of preterm delivery can significantly reduce the incidence of preterm-related complications, such as respiratory distress syndrome and necrotizing enterocolitis. However, ACS may have adverse effects on multiple systems including nervous system, cardiovascular system and carbohydrate metabolism in preterm infants. Whether ACS could influence neonatal development is still controversial. On this account, this review, focusing on short- and long-term effects of ACS therapy on nervous, cardiovascular, endocrine and other systems of infants born prematurely, will help clinical management and scientific research.