Progress in treatment of bronchopulmonary dysplasia with exosomes
10.3760/cma.j.cn113903-20220324-00284
- VernacularTitle:外泌体治疗支气管肺发育不良的研究进展
- Author:
Feifei PAN
1
;
Dong HUANG
Author Information
1. 贵州医科大学附属人民医院儿童重症医学科,贵阳 550000
- Keywords:
Bronchopulmonary dysplasia;
Exosomes;
Cell- and tissue-based therapy
- From:
Chinese Journal of Perinatal Medicine
2022;25(12):1010-1014
- CountryChina
- Language:Chinese
-
Abstract:
Bronchopulmonary dysplasia (BPD) is a poor-prognosis disease. Stem cells may be the only treatment that can promote the repair and reconstruction of damaged lungs through secreting exosomes. Exosomes play crucial roles in anti-inflammatory, anti-apoptosis, anti-oxidation, inhibiting pulmonary fibrosis and promoting regeneration of damaged lung tissues, which are expected to be a new candidate for the prevention and treatment of BPD. This article reviews the research progress in the treatment of BPD with exosomes.