Ureaplasma parvum-induced peritoneal dialysis-associated peritonitis: a case report

VernacularTitle:细小脲原体导致腹膜透析相关性腹膜炎1例
Author: Chao XIE ¹ ; Peiyi YE ; Cuixia WU ; Cuiyan YU ; Yaozhong KONG
Author Information

1. 佛山市第一人民医院肾内科，佛山　528000
Keywords: Ureaplasma; Peritoneal dialysis; Peritonitis; Metagenomics next- generation sequencing; Pathogen
From: Chinese Journal of Nephrology 2023;39(6):471-472
CountryChina
Language:Chinese
Abstract: Pathogen detection is very important to improve the prognosis of patients with peritoneal dialysis-associated peritonitis. The paper reported a case of peritonitis caused by Ureaplasma parvum diagnosed by metagenomics next-generation sequencing（mNGS）technology. The patient was a middle-aged woman and hospitalized due to abdominal pain and muddy effluent. Anti-infective treatments such as ceftazidime and vancomycin were given but the effect was poor. The result of traditional culture was negative. Ureaplasma parvum was detected by mNGS. After using doxycycline，the patient's inflammation was controlled. It is suggested that mNGS plays an important role in the detection of the pathogens in peritoneal dialysis-associated peritonitis patients with negative culture. Through this case report and literature review，clinical experience is provided for the diagnosis and treatment in such patients.