Bactericidal permeability increasing protein-anti-neutrophil cytoplasmic antibody- associated vasculitis complicated with bronchiectasis: a case report and literature review
10.3760/cma.j.cn441217-20220621-00630
- VernacularTitle:杀菌通透性增强蛋白-抗中性粒细胞胞质抗体相关性血管炎合并支气管扩张1例并文献复习
- Author:
Weili GAN
1
;
Zhizhi HU
;
Qiaodan ZHOU
;
Rui ZENG
Author Information
1. 华中科技大学同济医学院附属同济医院肾内科，武汉 430030
- Keywords:
Anti-neutrophil cytoplasmic antibody-associated vasculitis;
Bronchiectasis;
Bactericidal permeability increasing protein
- From:
Chinese Journal of Nephrology
2023;39(6):461-464
- CountryChina
- Language:Chinese
-
Abstract:
Anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis is a group of systemic small vasculitis characterized by the detection of ANCA in serum. Bactericidal permeability enhancing protein (BPI) is one of the target antigens of ANCA. BPI-ANCA-associated vasculitis is not common clinically, and the combination of bronchiectasis is not accidental. The paper reported a case of BPI-ANCA-associated vasculitis with renal damage combined with bronchiectasis. We reviewed relevant literature to explore the characteristics of BPI-ANCA-associated vasculitis and the correlation between bronchiectasis and ANCA-associated vasculitis, so as to improve the clinician's understanding on this disease.
