A case of podocyte infolding glomerulopathy

VernacularTitle:足细胞内陷性肾小球病1例
Author: Mengting JIA ¹ ; Ling ZHOU ; Jianzhong LI ; Lei SHEN ; Guoyuan LU ; Yanping SHEN
Author Information

1. 苏州大学附属第一医院肾内科，苏州　215006
Keywords: Nephrotic syndrome; Biopsy; Podocytes; Podocyte infolding glomerulopathy
From: Chinese Journal of Nephrology 2023;39(2):142-144
CountryChina
Language:Chinese
Abstract: Podocyte infolding glomerulopathy (PIG) is a pathologic type of podocyte glomerulopathy reported recently. The characteristic is that the ultrastructure related to podocytes, such as microspheres and microtubules, are folded into the glomerular basement membrane (GBM) under electron microscope. At present, there are few reports about this disease at home and abroad, and most of them are concentrated in Japan. The clinical characteristics and pathogenesis of PIG are still unclear. In this paper, we report a case of clinical manifestations of nephrotic syndrome, renal biopsy indicated PIG, after the treatment of glucocorticoid, hydroxychloroquine and tacrolimus, the patient's clinical symptoms were relieved and urinary protein decreased.