Evolution of no evidence of disease activity therapeutic goals of multiple sclerosis from new progress of nerve injury mechanisms
10.3760/cma.j.cn113694-20221205-00906
- VernacularTitle:从多发性硬化神经损伤机制新进展看无疾病活动证据治疗目标的演变
- Author:
Linjun CAI
1
;
Ying ZHANG
;
Xiaofei WANG
;
Lingyao KONG
;
Hongyu ZHOU
Author Information
1. 四川大学华西医院神经内科，成都 610041
- Keywords:
Multiple sclerosis;
Nerve injury;
Mechanism;
Disease-modifying therapy;
No evidence of disease activity
- From:
Chinese Journal of Neurology
2023;56(9):1060-1066
- CountryChina
- Language:Chinese
-
Abstract:
Multiple sclerosis is a severe autoimmune inflammatory disease mainly involving the central nervous system. In recent years, the exploration of the mechanism of nerve injury in multiple sclerosis has made great progress. At the same time, disease-modifying therapeutic drugs with different targets are also emerging. Understanding of the mechanisms of nerve injury in multiple sclerosis can help clinicians comprehensively understand the evolution of disease-modifying therapeutic targets of this disorder. Here, the mechanisms of nerve injury in multiple sclerosis and the relationship with the evolution of disease-modifying therapeutic targets are reviewed.
