Research progress of Cryptococcus gattii meningitis with different immune status
10.3760/cma.j.cn113694-20220830-00663
- VernacularTitle:不同免疫功能状态格特型隐球菌性脑膜炎的研究进展
- Author:
Kai DAI
1
;
Zhihui SU
;
Bang′e QIN
;
Fuhua PENG
;
Ying JIANG
Author Information
1. 中山大学附属第三医院神经内科，广州 510630
- Keywords:
Cryptococcus gattii;
Cryptococcal meningitis;
Immune function;
Genotype
- From:
Chinese Journal of Neurology
2023;56(5):566-571
- CountryChina
- Language:Chinese
-
Abstract:
Cryptococcus gattii is a kind of Cryptococcus that infects the lungs and central nervous system through the inhalation of infectious particles such as spores or Cryptococcus yeast cells. The development of clinical disease of Cryptococcus gattii may be determined by the sex, immunity and genetics of the host factors, in which immune system factors play an important role in host injury. Their defects will have serious clinical consequences. Cryptococcus gattii mainly infects the population with normal immune, and the infection of immunosuppressed population is rare. The infection mechanism, molecular types, clinical characteristics, treatment and prognosis of Cryptococcus gattii meningitis were different between the two populations. This article reviews the main differences in different immune status with Cryptococcus gattii meningitis.
