Combined central and peripheral demyelination after varicella-zoster virus infection: a case report
10.3760/cma.j.cn113694-20220816-00622
- VernacularTitle:水痘-带状疱疹病毒感染后中枢和周围神经联合脱髓鞘疾病1例
- Author:
Lili ZHANG
1
;
Menghan HU
;
Min WANG
;
Xungang FENG
;
Yuzhong WANG
Author Information
1. 济宁医学院附属医院神经内科,济宁 272029
- Keywords:
Demyelinating diseases;
Varicella-zoster virus;
Neurofascin
- From:
Chinese Journal of Neurology
2023;56(4):434-437
- CountryChina
- Language:Chinese
-
Abstract:
Combined central and peripheral demyelination (CCPD) is a rare autoimmune disease and its action mechanism remains unknown. This article described a case of CCPD with anti-neurofascin 155 IgG4 antibodies after varicella-zoster virus (VZV) infection who was recovered after steroids and intravenous immunoglobulin treatments. The clinical characteristics of this patient were summarized and the possible pathogenesis was discussed, so as to provide information of CCPD after VZV infection for clinicians.