A case of primary T cell lymphoma of the liver presented as FUO.
- Author:
Tae Hyung KIM
1
;
Hwi Joong YOON
;
Myung Im KIM
;
Jeoung Hun KIM
;
Si Young KIM
;
Kyung Sam CHO
;
Young Woon JANG
;
Yong Koo PARK
;
Juhie LEE
;
Dong Ho LEE
;
Sang Mok LEE
Author Information
1. Department of Internal Medicine, Kyung Hee University College of Medicine, Seoul, Korea.
- Publication Type:Case Report
- Keywords:
Lymphoma;
T-cell;
Hepatic;
Fever of unknown origin
- MeSH:
Adolescent;
Biopsy;
Doxorubicin;
Drug Therapy;
Female;
Fever;
Fever of Unknown Origin;
Humans;
Liver*;
Lymphoid Tissue;
Lymphoma;
Lymphoma, Non-Hodgkin;
Lymphoma, T-Cell*;
Magnetic Resonance Imaging;
Shock, Cardiogenic;
T-Lymphocytes;
Tomography, X-Ray Computed;
Ultrasonography;
Vincristine
- From:Korean Journal of Medicine
2001;60(3):260-265
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Primary non-Hodgkin's lymphoma of the liver, an organ normally devoid of a native lymphoid tissue, is very rare. We report a case of primary hepatic T-cell lymphoma in a 18-year-old girl, with review of literature. The pateint admitted with fever for 5 months. The ultrasonography revealed a 10 x 7 cm sized mass in the left lobe of the liver. On abdominal CT, the mass was poorly enhancing and low attenuated. On MRI, the signal intensity of the mass was low in T1 weighted image, heterogeneously high in T2 weighted image, and peripherally enhanced in contrast enhancing T1 weighted image. The biopsy specimen obtained by laparatomy showed anaplastic tumor. The malignant cells were positive for T-cell lineage (CD3, CD44, CD45RO). There was no evidence of the lymphoma in other regions. The patient was treated with CHOP (cyclophosphamide, adriamycin, vincristine and prednisolone) chemotherapy without objective response. The patient died of sudden cardiogenic shock.