A case of ischemic stroke in a young adult caused by combined defects of protein C and protein S and noncompaction of the ventricular myocardium
10.3760/cma.j.cn113694-20220826-00648
- VernacularTitle:蛋白C、蛋白S联合缺陷合并心肌致密化不全致青年缺血性卒中1例
- Author:
Kaiwei CAI
1
;
Yan DING
;
Peijie DU
;
Jiali GAO
;
Pingping SONG
;
Anding XU
;
Heng MENG
Author Information
1. 暨南大学附属第一医院神经内科，广州510630
- Keywords:
Stroke;
Brain ischemia;
Myocardium;
Adult;
Embolism
- From:
Chinese Journal of Neurology
2023;56(3):329-333
- CountryChina
- Language:Chinese
-
Abstract:
Ischemic stroke in young adults has attracted more and more attention due to the diversity of its etiology. Although atherosclerosis is the most common cause of stroke in young adults, other or unknown causes are not uncommon . To improve clinicians′ understanding of the etiological diagnosis of stroke in young adults, this article reports a case of ischemic stroke in the First Affiliated Hospital of Jinan University. The patient was a 22-year-old male with acute onset who was diagnosed with acute ischemic stroke based on clinical presentation, physical examination, and magnetic resonance imaging of the brain. After actively searching for the cause, laboratory and genetic tests revealed that the patient had inherited thrombophilia (protein C and protein S deficiency), and cardiac magnetic resonance imaging examination found that the patient had noncompaction of the ventricular myocardium.
