Research advances in chronic inflammatory demyelinating polyradiculoneuropathy
10.3760/cma.j.cn113694-20220613-00478
- VernacularTitle:慢性炎性脱髓鞘性多发性神经根神经病的研究进展
- Author:
Cuili MA
1
;
Yuzhong WANG
Author Information
1. 济宁医学院临床医学院，济宁272029
- Keywords:
Polyradiculoneuropathy, chronic inflammatory demyelinating;
Biological markers;
Diagnosis;
Pathogenesis
- From:
Chinese Journal of Neurology
2023;56(2):233-240
- CountryChina
- Language:Chinese
-
Abstract:
Chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) is a chronic autoimmune disease affecting the peripheral nervous system mediated by cellular and humoral immunity, characterized by limb weakness and sensory impairment. The main feature of CIDP by electrophysiological and pathological examinations is the demyelination of peripheral nerves. First-line treatment for CIDP includes glucocorticoids, intravenous immunoglobulins, and plasmapheresis. Some patients respond to current treatment not well and have a poor prognosis. Progress in the pathogenesis, diagnosis, and treatment of CIDP worldwide was reviewed in this article, aiming to provide references for the clinical diagnosis and treatment of CIDP.
