Research progress on cognitive dysfunction and brain gray matter areas changes in patients with obstructive sleep apnea hypopnea syndrome
10.3760/cma.j.cn113694-20220506-00363
- VernacularTitle:阻塞性睡眠呼吸暂停低通气综合征患者认知障碍与脑灰质区改变研究进展
- Author:
Lu JIN
1
;
Qiong WU
;
Ke NING
;
Yubing SUN
;
Jialing LIU
;
Jing LI
;
Yongzhong LIN
Author Information
1. 大连医科大学附属第二医院神经内科，大连116023
- Keywords:
Sleep apnea, obstructive;
Cognition disorders;
Gray matter
- From:
Chinese Journal of Neurology
2023;56(1):94-100
- CountryChina
- Language:Chinese
-
Abstract:
Obstructive sleep apnea hypopnea syndrome (OSAHS) is a sleep breathing disorder caused by obstruction of the upper airway during sleep from various causes. At present, the diagnosis and treatment of OSAHS are insufficient. OSAHS causes cognitive decline due to excessive oxidative stress and inflammatory response caused by sleep breathing disorder, and its alteration of the brain gray matter area may be related to cognitive dysfunction. This review investigates the correlation between cognitive dysfunction and brain gray matter areas changes in OSAHS, and elucidates the underlying mechanisms, which provide a theoretical basis for early clinical diagnosis and treatment.
