The non-communicating intracranial-extracranial Rosai-Dorfman disease: a case report
10.3760/cma.j.cn113694-20220413-00295
- VernacularTitle:颅内外非沟通性Rosai-Dorfman病1例
- Author:
Chi FENG
1
;
Zhiming CHEN
;
Liang CHEN
;
Junrong LEI
;
Jun QIN
;
Lei MOU
Author Information
1. 十堰市太和医院神经肿瘤疾病诊疗中心，十堰 442000
- Keywords:
Histiocytosis, sinus;
Magnetic resonance imaing;
Pathology, clinical;
Immunohistochemistry
- From:
Chinese Journal of Neurology
2023;56(1):78-81
- CountryChina
- Language:Chinese
-
Abstract:
Rosai-Dorfman disease (RDD) is a benign self-limited disease characterized by lymphadenopathy and phagocytosis of lymphocytes by histiocytes. A case of intracranial-extracranial non communicating RDD was reported in this paper. The patient was admitted to Shiyan Taihe Hospital in May 2020 because of "the left top scalp tumor was found for 4 months, and the right lower limb was numb for more than half a month". The plain scan and enhanced scan of the patient′s head magnetic resonance imaging (MRI) showed that the disease focus of the left parietal bone was slightly uneven enhanced, its internal and external soft tissues were significantly enhanced, and the local internal and external soft tissues were significantly thickened irregularly, with the size of about 3.2 cm× 4.7 cm, and adjacent brain parenchyma was compressed. After resection of left top mass and intracranial mass, pathological results showed spindle cell proliferation with inflammatory reaction, and immunohistochemical staining results supported the diagnosis of RDD. The neurological function of the patient recovered to normal basically 7 months after operation, and no recurrence of the disease was found in the MRI examination of the head. The treatment effect was satisfactory.
