Prevalence and risk factors of diabetic kidney disease in plain-sand areasand loess hilly areas of Gansu province
10.3760/cma.j.cn114798-20221122-01106
- VernacularTitle:甘肃省平原风沙与黄土丘陵地区糖尿病肾脏疾病患病情况及危险因素分析
- Author:
Jianning YANG
1
;
Doudou HONG
;
Jinxing QUAN
;
Limin TIAN
;
Yunfang WANG
;
Jing YU
;
Zibing QIAN
;
Panpan JIANG
;
Changhong DONG
;
Qian GUO
;
Jing LIU
;
Qi ZHANG
Author Information
1. 甘肃中医药大学第一临床医学院，兰州 730000
- Keywords:
Diabetes mellitus, type 2;
Diabetic nephropathies;
Risk factors;
Geographic locations
- From:
Chinese Journal of General Practitioners
2023;22(8):810-817
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the risk factors of diabetic kidney disease (DKD) in type 2 diabetes mellitus (T2DM) patients in plain-sand areas and loess hilly areas of Gansu province.Methods:A total of 1 599 T2DM patients who participated in chronic disease and risk factors monitoring and basic public health service management were selected by multi-stage stratified random sampling method in the sandy plain areas and loess hilly areas of Gansu province. Questionnaire survey, physical measurement and laboratory tests were performed. Multivariate binary logistic model was used to analyze the influencing factors.Results:The prevalence of DKD was 22.1% (174/787) among T2DM patients in the sandy plain areas and 19.1%(155/812) in the loess hilly area, respectively. Hypertension ( OR=3.022), hyperuricemia ( OR=2.114) and HbA1c≥7%( OR=2.231) were the risk factors for DKD in the plain-sand areas, and the risk of DKD increased with age. In the loess hilly areas, female sex ( OR=0.379) was the protective factor for DKD; while duration of disease≥10 years ( OR=2.476), hyperuricemia ( OR=1.907), HbA1c≥7% ( OR=1.927) were the risk factors for DKD; and the risk of DKD increased with the increase of age, and decreased with the increase of per capita monthly income. Conclusions:The prevalence of DKD and its influencing factors are different between sandy plain areas and loess hilly areas in Gansu province. The prevention and treatment of hypertension should be given more attention in sandy plain areas. In addition, the screening of DKD should be conducted among T2DM patients, particularly for those with old age, hyperuricemia and HbA1c≥7% in both areas of the province.
