Related factors of three-vessel disease in patients with stable coronary artery disease
10.3760/cma.j.cn114798-20230111-00047
- VernacularTitle:稳定性冠心病患者发生冠状动脉三支血管病变的相关因素分析
- Author:
Yajun ZHAO
1
;
Xuelin CHENG
;
Ming LIU
;
Xiaopan LI
;
Jing ZHOU
;
Jian ZOU
;
Yuxiang DAI
;
Sunfang JIANG
Author Information
1. 复旦大学附属中山医院全科医学科，上海 200032
- Keywords:
Coronary disease;
Uric acid;
High-density lipoprotein cholesterol;
Related factors
- From:
Chinese Journal of General Practitioners
2023;22(4):394-398
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To analyze the risk factors of three-vessel disease (TVD) in patients with stable coronary artery disease (SCAD).Methods:The clinical data of 447 patients with SCAD diagnosed in Zhongshan Hospital from May 2019 to April 2020 were retrospectively analyzed, including 108 cases with the single-vessel disease (SVD), 136 cases with the two-vessel disease, and 203 cases with three-vessel disease. The general data and hematological indexes were compared between patients with SVD and those with TVD; the related factors for TVD in SCAD patients were analyzed with univariate and multivariate logistic regression.Results:There were 244 males (78.5%) and 67 females (21.5%) with a median age of 57 years (64, 69). Univariate analysis showed that there were significant differences in diabetes history ( χ2=7.75, P=0.005), uric acid ( Z=-2.10, P=0.036), glycosylated hemoglobin ( Z=-2.77, P=0.006) and high density lipoprotein cholesterol (HDL-C) ( Z=-2.99, P=0.003) levels between SVD and TVD groups. Multivariate analysis showed that the high level of blood uric acid ( OR=1.01, 95% CI: 1.00-1.01, P<0.05) and the low level of HDL-C ( OR=3.29, 95% CI:1.23-8.85, P<0.05) were related risk factors of TVD. Conclusion:High blood uric acid level and low HDL-C level are related factors for TVD in patients with SCAD.
