Pregnancy complicated with primary hyperparathyroidism: a report of 3 cases
10.3760/cma.j.cn114798-20220714-00676
- VernacularTitle:妊娠合并原发性甲状旁腺功能亢进症3例
- Author:
Ziqi GE
1
;
Zili ZHANG
;
Qiuhong YANG
;
Yan LI
;
Xiaoping LI
;
Min SONG
Author Information
1. 济南市妇幼保健院产科，济南 250218
- Keywords:
Primary hyperparathyroidism;
Hypercalcemia;
Pregnancy
- From:
Chinese Journal of General Practitioners
2023;22(2):194-196
- CountryChina
- Language:Chinese
-
Abstract:
Clinical data of 3 pregnant women with primary hyperparathyroidism admitted in Jinan Maternal and Child Health Hospital from 2013 to 2021 were retrospectively reviewed. Hyperparathyroidism was diagnosed during pregnancy in all 3 cases. The clinical manifestations were non-specific, such as nausea, vomiting, anorexia, and fatigue. Patients also had gallbladder stones (1 case), gallbladder polyps (1 case), and renal parenchyma changes (2 cases). The hypercalcemia crisis occurred in all 3 cases, the blood Ca 2+ levels were 4.11 mmol/L, 2.92-3.82 mmol/L and 3.49-4.10 mmol/L, respectively; and preeclampsia developed in 2 cases. Sudden death occurred in case 1 who did not receive effective treatment during pregnancy; blood calcium was well controlled during pregnancy in case 2, and her neonate had hypocalcemia with good prognosis; case 3 underwent surgical treatment in early pregnancy, and then had missed abortion. Pathological examination revealed parathyroid tumors in all 3 cases.
