Liver transplantation for liver metastasis of unresectable rectal cancer: one case report
10.3760/cma.j.cn421203-20230207-00027
- VernacularTitle:肝移植治疗不可切除性直肠癌肝转移1例
- Author:
Chao SUN
1
;
Peng ZHANG
;
Shuyong MO
;
Yanfeng WANG
Author Information
1. 武汉大学中南医院，武汉大学肝胆疾病研究院，武汉大学移植医学中心，移植医学技术湖北省重点实验室，武汉 430071
- Keywords:
Liver transplantation;
Liver metastasis;
Colorectal cancer
- From:
Chinese Journal of Organ Transplantation
2023;44(6):366-369
- CountryChina
- Language:Chinese
-
Abstract:
This report described one case of applying liver transplantation (LT) in for liver metastases of unresectable rectal cancer.The recipient had multiple intrahepatic metastases upon a diagnosis of colorectal cancer.FOLFOX chemotherapy plus bevacizumab targeted therapy were offered after a resection of primary lesion.Two years later, intrahepatic metastases expanded while no extrahepatic metastasis or in situ recurrence was noted.After LT, tacrolimus + sirolimus immunosuppression regimen and chemotherapy of rhatitrexed were prescribed.Tumor recurred at 3 years after LT and the survival time was 6 years.For patients with unresectable liver metastases of colorectal cancer, LT in the absence of orthotopic recurrence and other distant metastases may improve patient quality-of-life and achieve better outcomes.
