A novel technique of pure transperitoneal laparoscopic nephroureterectomy at a single position for native upper tract urothelial carcinoma in ipsilateral renal transplant recipients
10.3760/cma.j.cn421203-20221107-00290
- VernacularTitle:单一体位经腹腔入路完全腹腔镜下治疗移植肾同侧自体上尿路上皮癌的临床研究
- Author:
Xiaoyong YANG
1
;
Zejia SUN
;
Wei WANG
;
Liang REN
;
Hang LIU
;
Wei WANG
;
Xiaodong ZHANG
;
Xiaopeng HU
Author Information
1. 首都医科大学附属北京朝阳医院泌尿外科，北京 100020
- Keywords:
Kidney transplantation;
Laparoscopy;
Nephroureterectomy;
Urothelial carcinoma
- From:
Chinese Journal of Organ Transplantation
2023;44(6):354-359
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To explore the techniques and outcomes of pure laparoscopic native nephroureterectomy (LNUT) with ipsilateral allograft at a single position for upper tract urothelial carcinoma (UTUC) in renal transplant (RT) recipients.Methods:Clinical data were retrospectively reviewed for 12 renal transplant children undergoing native UTUC with ipsilateral allograft from January 2016 to December 2021.There were 4 boys and 8 girls.Complete LNUT was performed with bladder cuff resection at a single position via a transperitoneal approach.The interval between UTUC and RT was 12-146 months.There were 6 pelvic UCs and 6 ureter UCs.Results:All laparoscopic procedures were successfully completed without any serious perioperative complication.Postoperative pathological examination confirmed the diagnosis of urothelial carcinoma.And all surgical margins were negative.One patient experienced an elevation of creatinine after one cycle chemotherapy and normalized after withdrawing chemotherapy.The median follow-up period was (4-65) month.Two cases of contralateral native transitional cell carcinoma had radical nephroureterectomy two years later and another two cases underwent transurethral resection of bladder tumor one year later.One case died from tumor metastasis.The remainders had no tumor recurrence or metastasis during follow-ups.Conclusions:Complete single-position LNUT for UTUC with ipsilateral allograft is a safe and effective mini-invasive technique.Effectively avoiding the injury of allograft, it also offers the advantages of standard operation, minimal trauma, simple handling and enhanced recovery after surgery (ERAS).
