Mechanical circulation support device as a bridging tool for heart transplantation recipients with refractory heart failure
10.3760/cma.j.cn421203-20220824-00212
- VernacularTitle:机械辅助循环桥接心脏移植在难治性心力衰竭中的应用
- Author:
Yangfeng TANG
1
;
Jiajun ZHANG
;
Bailing LI
;
Jun WANG
;
Xingli FAN
;
Guangwei ZHOU
;
Zhiyun XU
;
Lin HAN
Author Information
1. 海军军医大学附属长海医院心血管外科，上海 200433
- Keywords:
Heart transplantation;
Mechanical circulation support devices;
Extracorporeal membrane oxygenation
- From:
Chinese Journal of Organ Transplantation
2023;44(3):178-182
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To explore the clinical outcomes of recipients with refractory heart failure requiring an insertion of mechanical circulation support(MCS)device prior to heart transplantation(HT).Methods:From March 2017 to December 2021, retrospective review is performed for clinical data of 7 recipients with refractory heart failure requiring a bridging placement of MCS.There are 2 males and 5 females with an average age of(39.0±16.3)years(7~56 years)and an average weight of(57.6±19.9)kg(7~56 kg).The primary diseases of recipients are dilated cardiomyopathy(4 cases)severe viral myocarditis(2 cases)and ischemic cardiomyopathy(1 case).All of them develope acute decompensation of congestive heart failure.Before implanting MCS, two or more inotropic drugs are offered at maximal doses ages or IABP device, 6 cases required cardio-pulmonary resuscitation treatment and another patient for Heartcon assistance.All the patients bridge to heart transplatation.Results:Adjuvant therapy of MCS was offered for(20.0±11.5)d(7~34 d).Emergency HT is performed.Two post-HT deaths occurr due to multiple organ failure(1 case)and severe infection(1 case).The remainders recover smoothly during a follow-up period of(6~24 months).Conclusions:MCS device is recommended as a bridging too for HT recipients with refractory heart failure.It is imperative to improve clinical outcomes with MCS support before an onset of multiple organ dysfunction.Despite a perioperative mortality, long-term prognosis is generally satisfactory.
