Recent advances in preclinical research of renal xenotransplantation and selection of potential recipients in the future
10.3760/cma.j.cn421203-20220901-00229
- VernacularTitle:异种肾移植临床前研究进展及未来潜在受者选择
- Author:
Yuhao TU
1
;
Hao FENG
;
Lan ZHU
;
Gang CHEN
Author Information
1. 华中科技大学同济医学院附属同济医院器官移植研究所器官移植教育部重点实验室国家卫生健康委员会器官移植重点实验室 中国医学科学院器官移植重点实验室，武汉 430030
- Keywords:
Kidney transplantation;
Xenotransplantation;
Immune rejection;
Gene editing;
Immune suppression
- From:
Chinese Journal of Organ Transplantation
2023;44(2):122-128
- CountryChina
- Language:Chinese
-
Abstract:
After continuous efforts from generations of transplant surgeons, kidney transplantation (KT) has become an optimal treatment for end-stage renal disease.However, an imbalance between supply and demand of organs has always restricted the development of KT.For this clinical dilemma, xenotransplantation is expected to become one practical alternative for alleviating organ shortage.This review summarized recent literature reports of kidney xenotransplantation and the latest cases of pig-to-human kidney and heart transplantations.Also clinical transformations and applications of kidney xenotransplantation were discussed.
