Acute-on-chronic liver failure treated by split liver transplantation:a single-center experience on 9 cases
10.3760/cma.j.cn113855-20221028-00661
- VernacularTitle:劈离式肝移植治疗慢加急性肝功能衰竭9例
- Author:
Wei JIANG
1
;
Yuying SHAN
;
Shuqi MAO
;
Xi YU
;
Shengdong WU
;
Jiongze FANG
;
Jing HUANG
;
Changjiang LU
;
Caide LU
Author Information
1. 宁波市医疗中心李惠利医院肝胆胰外科，宁波 315041
- Keywords:
Liver transplantation;
Acute-on-chronic liver failure
- From:
Chinese Journal of General Surgery
2023;38(6):423-428
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To evaluate the short-term efficacy of split liver transplantation (SLT) in patients with acute-on-chronic liver failure (ACLF).Methods:The clinical data of 9 ACLF patients receiving SLT in our center from Mar 2021 to May 2022 were retrospectively analyzed to evaluate its safety and efficacy.Results:The preoperative APASL ACLF Research consortium (AARC) score of the 9 ACLF patients was 8 points in 1 case, 9 points in 3 cases, 10 points in 3 cases, 11 points in 1 case and 12 points in 1 case, 7 cases were in AARC-ACLF grade 2, and 2 cases in grade 3.In-situ liver splitting was performed in 9 deceased donors, including 4 classical split cases, 5 full size split cases. Among these 9 ACLF patients, 2 received left half liver transplantation, 3 received right half liver transplantation, and 4 received extended right lobe liver transplantation. After transplantation, all 9 recipients were discharged fully recovered, 1 case developed Clavien grade Ⅳa complication and 2 cases developed Clavien grade Ⅲb complication.After SLT treatment the median postoperative hospital stay was 27 days, the 1-year survival rate was 100%, and the organ survival rate was 88.9%.Conclusion:Split liver transplantation is a safe and feasible treatment method for ACLF patients.
